2Combine flour, brown sugar, butter, and salt in food processor; pulse mixture into coarse crumbs.
3Stir sugar, orange juice, tapioca, and cinnamon together in a bowl; add blueberries and stir to coat completely. Spoon blueberry mixture into a large baking dish. Sprinkle crumbs over the blueberries.
4Bake in preheated oven until topping is golden brown and the filling bubbles, about 40 minutes.